eClamp intracellular and patch clamp recording System

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Design

 

eClamp intracellular and patch clamp recording System

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eClamp is the best solution ever for intracellular and pach calmp recording

eCalmp is an all-in-one system incluing amplifier and clamp stimulator , analog to digital converter, separated  curent  stimulator , electrode impedance meter

You can  Design The best possible  stimulus protocol  by a digital pulse generator. 

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Features

 eClamp is the best  solution ever for   intracellular

and patch clamp recording  

  • Single electrode voltage and current clamp
  • Patch clamping
  • Single channel recording
  • Whole cell recording
  • Low noise
  • Software user interface
  • USB bus powerd design
  • High resolution analog to digital converter
  • Low weight and easy to use
  • Plug and Play (USB2 connector)
  • Operating voltage: 5V DC
  • Dimensions (w x h x d): 120 x 60 x 28 mm
  • Net weight 200g

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Specification

Data acquisition 
Processor 32 bit ,168MHz
FIFO Memory 64KB
Data transfer USB2

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Analog to digital converter Channel numners 1 Channel
ADC resolution 24bit
Linearity error ±7.6ppm (maximum)
Sample rate 100Ks/s per channel
Analog input range ±2.5v
Interface Serial
Isolation type Optical
Isolation voltage 2500V
Isolation resistance 10 12Ω

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Electrical  stimulator Mode Constant current, Unipolar, Isolated
Number of channels 1 Channels
Current range 0 to 4mA  or  0 to 20mA (optional)
Current resolution 1µA or 5µA (optional)
Output waveform DC or current pulse
current control Yes, software controll by 12 bit DAC
Current amplitude error 3LSB (maximum)
Polarity inversion Yes, software controll by Relay
Output switch Yes, software controll by Relay
Output voltage compliance 150V
Current rise time and delay 5μs, typical (1KΩ load)
Current fall time and delay 5μs, typical (1KΩ load)
Isolation type Optical
Isolation voltage 2500V
Isolation resistance 10 12Ω

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Microelectrode Amplifier
Amplifier Type Isolated, Intracellular
Number of channels 1 Channels
Gain 20
Input voltage range ±2.5V
Maximum analog input voltage ±2.5V
Input impedance 10 12Ω, common mode and differential
Input leakage current 60pA (typical)
Input capacitance 8pF
Common mode rejection ratio 75dB @ 50/60Hz
Isolation type Optical
Isolation voltage 2500V
Isolation resistance 10 12Ω
High cut filter 500, 1000,3000,5000, 10000Hz
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 Pulse generator       Experiment protocols  Single trial, Multi trial , Single protocol, Multi-protocol
 Stimulation Timing pattern  4
 Pattern parameters  Delay, Pulse duration, Pulse cycle, Pulse Numbers, Trial period, Trial Number
 Timing pattern resolution  10us
 Mixers  2ch Internal stimulator, 2ch Mechanical stimulator , 2ch Digital outs,
 Mixer Inputs  Pattern1, Pattern2, Pattern3, Pattern4, Digital Input1, Digital Input2
   

 

 

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Voltage Clamp

Selectable pulse amplitude
0 to ±1V
Selectable pulse duration 0.1 to 500ms
Selectable Seal test frequency 2 to 1000Hz
Recording Current range 0.2 pA to 200nA
Capacitance compensation Manual / Auto
Series resisance compensation Manual / Auto
 
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 Voltage Clamp    Selectable pulse amplitude  2nA to 200nA
Selectable pulse duration  0.1 to 500ms
Pipette Capacitance neutralization  Manual / Auto
Tuning frequency  2 to 1000Hz
Output offset-trimming  Auto
   
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 Requirements

CPU : 2core,  2Ghz,
memory : 2GB
Graphic : 1024,768
Audio : Internal or external sound card

PC
Operating System Windows 7
Software Dotnet Framework 4 or higher

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Compare Products

 

 

Product name

eWave8D/16D

eWave32-64-128D

eWave2S

eWave4S

electromodule

eLab2/4/8/16/32

eClamp

Price

5500$/

9500$

18500$/

35500$

 

 

     

 

 

Amplifier  Channel numbers

8/16

32/64/128

2+1

3+1

          1

     8/16/32

1

Amplifier Type

Differential, DC

Differential, DC

Differential, DC

Differential, DC

Differential, DC

Differential DC

DC

ADC resolution

24bit

24bit

24bit

24bit

24bit

24bit

24bit

Sample rate/ per channel

1Ks/s

500s/s

10Ks/s

5Ks/s

50Ks/s

30-50Ks/s

100Ks/s

Processor

32bit, 128MHz

32bit, 153MHz

32bit, 128MHz

32bit, 72MHz

FPGA

32bit, 168MHz

32bit,168MHz

Data Interface

USB2

Bluetooth wireless

WI-FI/USB2

 

USB2

USB2

Bluetooth wireless

USB2

USB2

USB2

Current Stimulator

No

No

Yes (5mA, 150V), 1 μA range

Yes (100mA, 350V)

Yes (4/20mA ,150V)

Yes (4/20mA ,150V)

Yes (4/20mA ,150V)

Gain

6

6

6

6

20

50

1

Digital inputs

2

2

2

2

2

2

2

Digital output

2

2

2

2

2

2

2

Analog  input

1

0

0

0

0

0

0

Analog output

1

0

0

0

0

0

0

Dimensions (L/H/W) mm

120x28x60

155x33x95

120x28x60

155x33x95

366x116x350 

120x28x60

120x28x60

inputs resistance

10Ω

10Ω

10Ω

10Ω

1012 Ω

1012 Ω

1012 Ω 

Battery life 

Re-chargeable

12 Hours

12Hours

12 Hours

12 Hours

5V adaptor–no Bat

5V  USB input –no Bat

5V  USB input –no Bat

Filter band

DC -500Hz

DC -250Hz

DC -5KHz

DC -2KHz

0.5Hz -3KHz

0.5Hz -10KHz

DC -10KHz

Application

EEG/ ECoG /ECG/EMG/

EOG

Yes

Yes

Yes

Yes

Yes

Yes

No

ERP

Yes-8/16ch

Yes -32/64/128ch

No

No

No

Yes

No

Sensors

EEG,EMG,ECG,BVP

Temp, Skin Resistance

 

Yes

 

 

Yes

 

No

 

No

 

No

 

No

 

No

LFP

No

No

Yes

Yes

Yes

Yes

No 

Single unit

No

No

No

No

Yes

Yes

No 

Intracellular recording, Patch Clamp (Voltage /Current)

No

No

No

No

No

No

Yes

 NCV

No

No

Yes

Yes

Yes

Yes

No

Kindling

No

No

Yes

Yes

Yes

Yes

No

VEP

No

No

Yes

Yes

Yes

Yes

No

Spike Sorter

No

No

No

No

Offline

Offline/Online

No

 

 

 

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